COVID-19 Induced Ulcerative Colitis: A Case Presentation and Review of Evidence

A 56-year old man presented to the hospital with a complaint of rectal bleeding, and sent home with a prescription for 1% hydrocortisone cream under the belief it was due to hemorrhoid irritation. He returned 6 months later with no resolution in symptoms, with the additive 1 month of watery diarrhea that transitioned to bloody diarrhea.  Lower endoscopy was significant for severe, diffuse inflammation from the ileum to the rectum characterized by granular, friable, and ulcerated mucosa. After a significant work-up indicating the diagnosis of Ulcerative colitis, UC, he disclosed this started when he was diagnosed in clinic with COVID-19. This case report will review previously investigated case reports with similar findings of Ulcerative colitis post COVID-19 infection.