- Home
- Volume 04 (2025), Version 11
- Combined Spinal-Epidural Anaesthesia for Lower Limb Orthopaedic Surger…
Combined Spinal-Epidural Anaesthesia for Lower Limb Orthopaedic Surgery-An Observational Study
Background: Combined spinal-epidural (CSE) anaesthesia has emerged as a preferred technique for major orthopaedic procedures. This study evaluates the effect of epidural top-up on spinal anaesthesia using the separate interspace method in total knee replacement surgeries. Material and Methods: A prospective observational study was conducted on 66 patients undergoing elective TKR. Sensory and motor blockade, haemodynamic changes, and postoperative analgesia were analysed across the spinal and epidural phases. Results: Epidural top-up significantly increased sensory blockade in 77.2% of patients. Motor blockade was sustained, and haemodynamic parameters remained stable. VAS scores remained low postoperatively, indicating effective pain control. Conclusion: The separate interspace CSE technique enhances sensory blockade, provides stable intraoperative conditions, and ensures effective postoperative analgesia, validating its use in prolonged orthopaedic procedures.
- Greene NM. Distribution of local anesthetic solutions within the subarachnoid space. Anesth Analg. 1985;64(7):715-30.
- Cousins MJ, Bridenbaugh PO. Neural blockade in clinical anesthesia and management of pain. 3rd ed. Lippincott-Raven; 1998.
- Curelaru I. Subarachnoid and epidural anesthesia: Long-term experience with combined techniques. Anesth Analg. 1980;59(7):439-46.
- Rawal N. Combined spinal-epidural anesthesia. Curr Opin Anaesthesiol. 1998;11(5):519-21.
- Becker DE, Reed KL. Local anesthetics: Review of pharmacological considerations. Anesth Prog. 2012;59(2):90-101.
- Liu SS, Strodtbeck WM, Richman JM, Wu CL. A comparison of regional versus general anesthesia for total hip arthroplasty: A meta-analysis. Anesth Analg. 2005;101(6):1638-45.
- Danninger T, Memtsoudis SG. Tranexamic acid and neuraxial anesthesia in joint arthroplasty: A review. Anesth Analg. 2014;118(2):202-8.
- Rodgers A, Walker N, Schug S, McKee A, Kehlet H, van Zundert A, et al. Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: Results from overview of randomised trials. BMJ. 2000;321(7275):1493.
- Brown DL. Spinal, epidural, and caudal anesthesia. In: Miller’s Anesthesia. 7th ed. Philadelphia: Churchill Livingstone; 2010.
- Kehlet H, Dahl JB. Anaesthesia, surgery, and challenges in postoperative recovery. Lancet. 2003;362(9399):1921-8.
- Matsushita T, Yamada Y, Inoue S, Tanaka Y. Enhancement of spinal block by epidural top-up: Pharmacokinetic and pharmacodynamic perspectives. J Anesth. 2020;34(5):726-32.
- Narayanasamy S, Vasanthakumar K, Kumari SA. Comparative evaluation of motor blockade in separate vs same interspace CSE technique in lower limb surgeries. Indian J Anaesth. 2021;65(3):212-8.
- Hartmann B, Junger A, Klasen J, Benson M, Jost A, Banzhaf A, et al. The incidence and risk factors for hypotension after spinal anesthesia induction: A meta-analysis. Anaesthesia. 2020;75(8):1064-73.
- Talke P, Tayefeh F, Sessler DI, Jeffrey R, Noursalehi M, Richardson C. Effects of epidural anesthesia on thermoregulatory responses. Anesthesiology. 2022;136(2):230-40.
- Aasen AO, Myhre HO, Soreide E. Complications related to combined spinal-epidural anaesthesia: A review of 5,000 cases. Acta Anaesthesiol Scand. 2019;63(6):745-52.